https://www.diazcuadroslab.org/research daily 0.75 2024-10-22 https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/cbdec0a1-ddf5-4ffa-8fb8-fcba1d80b5a1/Infographic.png Research Average gestation period and lifespan in select species. Courtesy of Ross Toro. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/3bf1cfc9-020b-40a6-a9d9-ce1070db4265/Otis%26Brent1954.jpg Research - Make it stand out Graphic representation of the difference in developmental rate between mouse and human embryos. Otis & Brent 1954. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/132bb706-e8e3-4463-ad60-03a5ef5f0732/giphy.gif Research - Make it stand out Oscillations of the segmentation clock (HES7-YFP) in human presomitic mesoderm cells derived in vitro. Diaz-Cuadros et al. 2020 https://www.diazcuadroslab.org/people daily 0.75 2026-07-28 https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/f8bdca94-9be2-4335-b4f7-969a40324189/20211022_092305.jpg People - Margarete Diaz Cuadros Group Leader Margarete is a Junior Fellow in the Department of Molecular Biology at Massachusetts General Hospital. She earned her Bachelor’s degree in biochemistry at Columbia University (2014) and was named class valedictorian. As an undergraduate, she worked in Dr. Martin Chalfie's laboratory investigating neuronal subtype differentiation in the nematode Caenorhabditis elegans. She later completed her PhD under the supervision of Dr. Olivier Pourquie at Harvard Medical School (2022). Her graduate research focused on the development of in vitro systems for the recapitulation of the mammalian segmentation clock based on pluripotent stem cells. Through a special fellow’s program, Margarete launched her independent research group directly after completion of her PhD. The Diaz Cuadros laboratory focuses on understanding the molecular and genetic basis of species-specific developmental rates by combining in vitro stem cell work with in vivo studies in C. elegans. Born and raised in Lima, Peru, Margarete enjoys cooking, baking, and looking after her vegetable garden. She was co-director of the Research Experience for Peruvian Undergraduates program for four years and currently serves on the Committee for the Advancement of Women in Science in Peru. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/34918776-b33b-44d5-b703-a5bc6c82acc0/Gabriel+Images_54.JPG People - Gabriel Valdebenito Postdoctoral Fellow Gabriel is a Postdoctoral Fellow in the Department of Molecular Biology. Gabe earned his bachelor's degree from UCSC, Chile, in 2015. He moved noth to Santiago to pursue a master’s degree in Human Physiology at the University of Chile (2017) and worked as part of the Endocrinology and Metabolism Laboratory, where he investigated the role of fatty acids in fetal muscle physiology. His academic journey took him to the United Kingdom, where he embarked on a Cell and Developmental Ph.D. program at Duchen Lab at University College London (2019-2024). Here, he became interested in the intricacies of mitochondrial primary diseases, focusing on nutrient sensing signaling, mitochondrial quality control pathways, and calcium signaling. As part of this program, Gabriel implemented a myogenic model derived from hiPSCs to gain a deeper understanding of the consequences of the m.3243A>G mutation in muscle physiology. Outside of the lab, he enjoys following tennis matches, exploring new places in Boston, and rewatching The Big Bang Theory, Modern Family, and Downton Abbey. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/f13dbaf4-b6d2-43dc-a878-5b97e2e0c98f/1009116219+copy.jpg People - Qingyuan Hu Postdoctoral Fellow Born in China, Qingyuan earned his PhD in developmental biology at the University of Chinese Academy of Sciences. His PhD focuses on the relationship between environmental conditions and C. elegans larval development. At Margarete's lab, he will continue investigating the genes that regulate the response of developmental speed to various environmental clues in C. elegans. Outside of the lab, he enjoys playing boxing, Brazilian Jujutsu, and practicing the acoustic guitar. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/668b26b3-e56f-413a-b4dd-045b5b888423/Xintao_headshot.jpg People - Xintao Zhu PhD Student Xintao Zhu is a PhD student at the University of Geneva, Switzerland. Originally from Neijiang, China, he earned his bachelor’s degree from Zhejiang Ocean University and his master’s degree in biology from the University of Geneva before continuing on to his doctoral studies. He is currently a Graduate Research Assistant in the Diaz Cuadros Lab at Massachusetts General Hospital, where he investigates the mechanisms underlying species-specific differences in developmental speed. Outside the lab, he enjoys cooking and exploring new cuisines, traveling to experience both nature and cultural history, working out, playing video games, and reading books on psychology, criminology, sociology and history. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/0a03e010-05a7-4ab8-bd66-6ce9155f5394/IMG_7555.jpeg People - Tucker Dammin Administrative Coordinator Tucker is the Sr. Administrative Coordinator (Temp) for the Diaz Cuadros, Strecker and Wattrus Labs. Tucker processes expenses, handles financial payments, places orders and performs other administrative tasks. Tucker is from Boston and lives in East Cambridge, and has previously worked for the MGB Neurology Education program, BWH Privacy Office and the MGH Cancer Center. Outside of work, he likes learning about climate topics and advocating for recycling and decarbonization, and enjoys being outdoors and cooking. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/d9307cce-cb60-473d-8b96-980a696d72ef/Sissi+Headshot+copy.jpg People - Sissi Chen Undergraduate Student Sissi is an undergraduate research assistant who is currently a student at Wellesley College (2026), where she is majoring in Neuroscience with a minor in Biology. In the Diaz Cuadros Lab, she will be working with the nematode Caenorhabditis elegans. In Wellesley College, she currently serves as an Unistellar astrophotographer for the Astrophysics department and is on the E-Board for Wellesley College’s Hip-Hop team Freestyle. From Beijing, China, Sissi enjoys dancing, jogging, drawing, photography/videography, reading, visiting museums, etc. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/a140dea1-3bc7-49ce-b1fe-52100869f571/carolina.jpg People - Carolina Mendez Undergraduate Student Carolina is a Co-Op research assistants in the Diaz-Cuadros Lab. She is currently a third year undergraduate student at Northeastern University, pursuing a BS in Cell and Molecular Biology. At Northeastern, she is also a Resident Assistant and a member of a few clubs around campus: The Latin American Student Organization (LASO), NU Sexual Health Advocacy, Resources, and Education (NUSHARE), and the Mexican Student Association (MEXSA). Outside of classes she likes to maintain her passion for ballet by taking a class about once a week. She used to be a dancer for 8 years! In the future, she hopes to apply all that she learns during her undergraduate career in the classroom and in the lab to attend medical school. https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/e4f8443d-1622-477e-9e39-c6c0c8ddc598/20210926_160200.jpg People - Moshi Fetch Specialist https://images.squarespace-cdn.com/content/v1/61b7c6fbecfe8757ee8b1db7/5fd5b80f-2dcd-43e9-8891-a2020df072cd/IMG_1692.jpg People - Sir Cornelius Stewart Introcaso I Chief of Hoperations. 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